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Microbial biosensors: A review

A microbial biosensor is an analytical device which integrates microorganism(s) with a physical transducer to generate a measurable signal proportional to the concentration of analytes. In recent years, a large number of microbial biosensors have been developed for environmental, food, and biomedical applications. Starting with the discussion of various sensing techniques commonly used in microbial biosensing, this review article concentrates on the summarization of the recent progress in the fabrication and application of microbial biosensors based on amperometry, potentiometry, conductometry, voltammetry, microbial fuel cell, fluorescence, bioluminescence, and colorimetry, respectively…

Readable and up-to-date overview of microbial biosensors. Excellent general overview of biosensors and transducer concepts. Survey of recent developments. Advantages: Microbes (e.g., algae, bacteria, and yeast) offer an alternative for the fabrication of biosensors because they can be mass produced through cell culturing. Also, compared to other cells from higher organisms such as plants, animals, and human beings, microbial cells are easier to manipulate and have better viability and stability in vitro. Disadvantages: Microbial biosensors typically suffer from poor selectivity because of the non-specific cellular response to substrates. Interesting general comments, for example: The detection of glucose accounts for about 85% of the entire biosensor market as of the publication of this report.

Liang Su, Wenzhao Jia, Changjun Hou, Yu Lei, “Microbial biosensors: A review,” Biosensors and Bioelectronics, Vol. 26, Iss. 5, 15 January 2011, p. 1788-1799

Expertise Level

Professional Field

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