Tag Archives: nanotechnology

A polysaccharide bioprotonic field-effect transistor

Abstract In nature, electrical signalling occurs with ions and protons, rather than electrons. Artificial devices that can control and monitor ionic and protonic currents are thus an ideal means for interfacing with biological systems. Here we report the first demonstration of a biopolymer protonic field-effect transistor with proton-transparent PdHx contacts. In maleic-chitosan nanofibres, the flow [...]

Assessment of social implications of nanotechnologies in Japan: Application of problem structuring method based on interview surveys and cognitive maps

Abstract This paper aims at developing a problem structuring method based on interview surveys of key stakeholders and a well-known visualizing technique, called a “cognitive map.” We found that this new method, based on an interactive process with key stakeholders, was able to draw broader and more detailed issues than was previously anticipated. We also [...]

Recent advances in polyaniline based biosensors

Abstract The present paper contains a detailed overview of recent advances relating to polyaniline (PANI) as a transducer material for biosensor applications. This conducting polymer provides enormous opportunities for binding biomolecules, tuning their bio-catalytic properties, rapid electron transfer and direct communication to produce a range of analytical signals and new analytical applications. Merging the specific [...]

Toxicity issues in the application of carbon nanotubes to biological systems

Abstract Carbon nanotubes (CNTs) have recently emerged as a new option for possible use in methodologies of cancer treatment, bioengineering, and gene therapy. This review analyzes the potential, through possible toxicologic implications, of CNTs in nanomedicine. Generally, proven success in other fields may not translate to the use of CNTs in medicine for reasons including [...]

Electrochemical sensing based on carbon nanotubes

Abstract The singular chemical structure and the size of carbon nanotubes (CNTs) provide their extraordinary properties. Many researchers have used the electronic characteristics of CNTs to develop electrochemical analytical methods and sensing devices with improved characteristics. In this overview, we discuss the most significant innovations in electrochemical sensing based on CNTs, as reported in the [...]

Array-based sensing with nanoparticles: ‘Chemical noses’ for sensing biomolecules and cell surfaces

Abstract Nanoparticle-based arrays have been used to distinguish a wide range of biomolecular targets through pattern recognition. In this report, we highlight new ‘chemical nose’ methodologies that use nanoparticle systems to provide high sensitivity sensing of biomolecular targets, including fluorescent polymer/gold nanoparticle complexes that can discriminate between different bioanalytes including proteins, bacteria, and mammalian cells [...]

Emerging synergy between nanotechnology and implantable biosensors: A review

Abstract The development of implantable biosensors for continuous monitoring of metabolites is an area of sustained scientific and technological interests. On the other hand, nanotechnology, a discipline which deals with the properties of materials at the nanoscale, is developing as a potent tool to enhance the performance of these biosensors. This article reviews the current [...]

Review of analytical figures of merit of sensors and biosensors in clinical applications

Abstract …Health care appears to provide the best opportunity for sensor development. Among the wide range of different sensors and biosensors, electrochemical biosensors are the most common in the clinical field, due to their high sensitivity and selectivity, portability, rapid response time and low cost. This article provides an up-to-date overview of the analytical performance [...]

Nano-Biosensor Development for Biomedical and Environmental Measurements

Abstract Nano biosensor development for biomedical and environmental measurements has been tried by research groups all over the world. Identifying and fabricating suitable nano-materials as enzyme immobilizing matrices to enhance characteristics of the sensor is the most important and difficult task of it. In this chapter we discuss about polypyrrole(PPy) nano-tube array grown on Alumina [...]

Development of Smart Functional Surfaces for Biosensor Applications

Abstract Biosensing platforms and antimicrobial coatings were developed to combat problems associated with infectious diseases. Particularly, a lytic bacteriophage based surface plasmon resonance (SPR) biosensor was developed to detect food borne pathogen Staphylococcus aureus (S.aureus) in real-time with high specificity. Lytic bacteriophages are naturally developed molecular probes that infect bacteria. They are environmentally stable and [...]