Tag Archives: physics

T-Ray Sensing and Imaging

Abstract Terahertz-ray (T-ray) wavelengths are long enough to pass through dry, nonpolar objects opaque at visible wavelengths, but short enough to be manipulated by optical components to form an image. Sensing in this band potentially provides advantages in a number of areas of interest to security and defense such as screening of personnel for hidden [...]

Surface acoustic wave biosensors: a review

Abstract This review presents an overview of 20 years of worldwide development in the field of biosensors based on special types of surface acoustic wave (SAW) devices that permit the highly sensitive detection of biorelevant molecules in liquid media…1987 saw the first approaches, which used either horizontally polarized shear waves (HPSW) in a delay line [...]

Direct optical sensors: principles and selected applications

Abstract In the field of bio and chemosensors a large number of detection principles has been published within the last decade. These detection principles are based either on the observation of fluorescence-labelled systems or on direct optical detection in the heterogeneous phase…Here, an overview of methods of microrefractometric and microreflectometric principles is given and benefits [...]

A multicomponent recognition and separation system established via fluorescent, magnetic, dualencoded multifunctional bioprobes

Abstract Accurate and rapid recognition and separation of multiple types of biological targets such as molecules, cells, bacteria or viruses from complex sample mixtures is of great importance for a wide range of diagnostic and therapeutic strategies. To achieve this goal, a set of fluorescent, magnetic, dual-encoded multifunctional bioprobes has been constructed by co-embedding different-sized [...]

Optical biosensors for probing at the cellular level: A review of recent progress and future prospects

Abstract New approaches are required to understand the complex processes taking place in the smallest unit of life. Recent years have seen an increasing activity in the use of optical devices and techniques for the investigation of the properties of single cells and also populations of cells including cell to cell communication. This article reviews [...]

Fast and accurate peanut allergen detection with nanobead enhanced optical fiber SPR biosensor

Abstract This paper is the first report of a fiber optic SPR biosensor with nanobead signal enhancement. We evaluated the system with a bioassay for the fast and accurate detection of peanut allergens in complex food matrices. Three approaches of an immunoassay to detect Ara h1 peanut allergens in chocolate candy bars were compared; a [...]