Tag Archives: synthetic olfaction

Olfactory receptor-based smell nanobiosensors: An overview of theoretical and experimental results

Abstract Mammalian olfactory system is the archetype of smell sensor devices. Its complexity resides both in the odorant mechanism of capture by the single olfactory receptor (OR) and in the space organization and codification of the information. The result is a unique profile for each odorant. Our aim is to partially mimick this system, in [...]

Mimicking nature’s noses: From receptor deorphaning to olfactory biosensing

Abstract The way in which organisms detect specific volatile compounds within their environment, and the associated neural processing which produces perception and subsequent behavioural responses, have been of interest to scientists for decades. Initially, most olfaction research was conducted using electrophysiological techniques on whole animals. However, the discovery of genes encoding the family of human [...]

Array-based sensing with nanoparticles: ‘Chemical noses’ for sensing biomolecules and cell surfaces

Abstract Nanoparticle-based arrays have been used to distinguish a wide range of biomolecular targets through pattern recognition. In this report, we highlight new ‘chemical nose’ methodologies that use nanoparticle systems to provide high sensitivity sensing of biomolecular targets, including fluorescent polymer/gold nanoparticle complexes that can discriminate between different bioanalytes including proteins, bacteria, and mammalian cells [...]